One chloro-furoeremophilanoid and two new natural dimers from Ligularia atroviolacea |
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| Authors: | Jun Zhao Hao Wu Ke Xin Huang Shu Yun Shi Hua Peng Xian Feng Sun Liu Rong Chen Qun Xiong Zheng Qi Jun Zhang Xiao Jiang Hao Joachim Stockigt Xiao Kun Li Yu Zhao Jia Qu |
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| Institution: | a Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China;b Key Laboratory of Southern Zhejiang TCM R&D, Pharmacy School of Wenzhou Medical College, Wenzhou 325035, China;c School of Chemical Engineering, Central South University, Changsha 410083, China;d Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China |
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| Abstract: | Three new compounds,including one chloro-furoeremophilanoid (1),one eremophiladiolide (2),a rare dimer of nor-furoeremophilanoid,ligulatrovine A (3),and a known furoeremophilanolide (4),were isolated from Ligularia atroviolacea.The structures of compounds 1-4 were elucidated by spectroscopic methods including ID and 2D NMR experiments as well as X-ray diffraction study. |
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| Keywords: | Natural sesquiterpene Eremophiladiolide Dimer Chloro-furanoeremophilane X-ray Ligularia atroviolacea |
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