| A New Synthetic Route for Preparation of 2-Chloro-6-fluoro-benzonitrile and 2-Chloro-6-fluorobenzoic Acid |
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| 引用本文： | XiaoYunLI QiongZHENG PengYU ChiHUANG JianLiDUAN JunQingPENG. A New Synthetic Route for Preparation of 2-Chloro-6-fluoro-benzonitrile and 2-Chloro-6-fluorobenzoic Acid[J]. 中国化学快报, 2004, 15(8): 895-898 |
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| 作者姓名： | XiaoYunLI QiongZHENG PengYU ChiHUANG JianLiDUAN JunQingPENG |
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| 作者单位： | [1]CollegeofChemistry,WuhanUniversity,Wuhan430072 [2]CollegeofPharmacy,WuhanUniversity,Wuhan430072 |
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| 摘 要： | An effective synthetic route for preparation of 2-chloro-6-fluorobenzonitrile, 2-chloro-6-fluorobenzamide and 2-chloro-6-fluorobenzoic acid has been described. It includes diazotization,fluorination, ammoxidation and hydrolysis reactions.
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| 关 键 词： | 合成 制备 2-氯-6-氟-氰苯 2-氯-6-氟苯甲酰胺 2-氯-6-氟苯甲酸 氨氧化作用 水解作用 |
A New Synthetic Route for Preparation of 2-Chloro-6-fluoro-benzonitrile and 2-Chloro-6-fluorobenzoic Acid |
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| Xiao Yun LI,Qiong ZHENG,Peng YU,Chi HUANG,Jian Li DUAN,Jun Qing PENGCollege of Chemistry,College of Pharmacy,Wuhan University,Wuhan. A New Synthetic Route for Preparation of 2-Chloro-6-fluoro-benzonitrile and 2-Chloro-6-fluorobenzoic Acid[J]. Chinese Chemical Letters, 2004, 15(8): 895-898 |
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| Authors: | Xiao Yun LI Qiong ZHENG Peng YU Chi HUANG Jian Li DUAN Jun Qing PENGCollege of Chemistry College of Pharmacy Wuhan University Wuhan |
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| Affiliation: | Xiao Yun LI,Qiong ZHENG,Peng YU,Chi HUANG,Jian Li DUAN,Jun Qing PENGCollege of Chemistry,College of Pharmacy,Wuhan University,Wuhan 430072 |
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| Abstract: | An effective synthetic route for preparation of 2-chloro-6-fluorobenzonitrile, 2-chloro-6-fluorobenzamide and 2-chloro-6-fluorobenzoic acid has been described. It includes diazotization, fluorination, ammoxidation and hydrolysis reactions. |
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| Keywords: | 2-Chloro-6-fluorobenzonitrile 2-chloro-6-fluorobenzamide 2-chloro-6-fluorobenzoic acid ammoxidation hydrolysis. |
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