Synthesis and neuroprotective properties of novel cinnamide derivatives |
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| Authors: | Bin Wu Li Zhou Hui Hui Cai |
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| Affiliation: | School of Pharmacy, Nanjing Medical University, Nanjing 210029, China |
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| Abstract: | A new series of compounds(E)-1-(4-(bis-arylmethyl)piperazin-1-yl)-3-arylprop-2-en-1-one(1a-r),have been synthesized and their structures were confirmed by ESI-MS and ~1H NMR.The preliminary pharmacological screening showed that some of these compounds had similar neuroprotective effects with Edaravone. |
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| Keywords: | Cinnamide derivatives Synthesis Neuroprotective Edaravone |
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