N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions |
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| Authors: | Pearson Anthony J Panda Santanu |
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| Institution: | Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA. ajp4@cwru.edu |
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| Abstract: | Proline anthranilamide-based pseudopeptides were shown to be effective organocatalysts for enantioselective direct aldol reactions of a selection of aldehydes with various ketones with excellent yield, enantioselectivity up to 99% and anti to syn diastereoselectivity up to 25:1. |
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