Some substitution and heterocyclization reactions based on 1,4-dihydropyridines |
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Authors: | I P Skrastin'sh G Ya Dubur |
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Institution: | (1) Institute of Organic Synthesis, Latvian Academy of Sciences, 226006 Riga |
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Abstract: | Data on the bromination, chlorination, and bromolactonization of 4-aryl-1,4-dihydropyridines are correlated. The reactions of the products of bromination of 4-aryl-1,4-dihydropyridines with various nucleophilic agents (amines and iodide, azide, and thiocyanate ions) and reactions involving the heterocyclization of the products of substitution of the 2,6-methyl groups of 4-aryl-1,4-dihydropyridines, which lead to condensed furo-, difuro-, pyrrolo-, dipyrrolo-, furopyrrolo-, and furothiazolopyridines and thiazolopyridothiadiazines are examined.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 781–791, June, 1992. |
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