Synthesis and conformational analysis of azacyclophanes from l-tyrosine |
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Authors: | Rodolfo Quevedo,Ismael Ortiz,André s Reyes |
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Affiliation: | Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Cra 30 N° 45-03 Bogotá, Colombia |
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Abstract: | The synthesis of a new azacyclophane formed by two l-tyrosine units joined by two methylene bridges is presented. The structural and conformational characteristics are briefly discussed. Spectroscopic and theoretical data reveal a syn structure with two intramolecular hydrogen bonds. |
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