A simple method for the oxidation of primary alcohols with o-iodoxybenzoic acid (IBX) in the presence of acetic acid |
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Authors: | Cheng-Kun Lin |
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Affiliation: | Department of Chemistry, National Chung-Hsing University, Taichung 40227, Taiwan ROC |
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Abstract: | A simple method for the oxidation of primary alcohols to aldehydes using o-iodoxybenzoic acid (IBX) with the addition of stoichiometric acetic acid has been developed. Addition of acetic acid significantly accelerated the reaction rate. Under these conditions, primary aliphatic, benzylic, and allylic alcohols are smoothly converted to aldehydes in high yields (90-97%). |
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Keywords: | o-Iodoxybenzoic acid (IBX) Oxidation Aldehydes |
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