One-pot three component α-aminoalkylation of conjugated nitroalkenes and nitrodienes |
| |
| Authors: | Kunjanpillai Rajesh |
| |
| Institution: | Department of Chemistry, Indian Institute of Technology, Bombay, Mumbai 400 076, India |
| |
| Abstract: | Nitroethylenes possessing aryl, heteroaryl, and alkyl substituents at the β-position as well as δ-substituted nitrobutadienes undergo facile aminoalkylation at the α-position upon treatment with formaldehyde and a secondary amine in the presence of imidazole and trifluoroacetic acid to afford α-aminoalkylated nitroalkenes and nitrodienes in good to excellent yield and stereoselectivity. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
