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Highly efficient synthesis of phenanthroquinolizidine alkaloids via Parham-type cycliacylation
Authors:Ziwen Wang
Affiliation:State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People’s Republic of China
Abstract:A concise and efficient route involving Parham-type cycliacylation as the key step has been used to synthesize phenanthroquinolizidine alkaloids 1a-c and 2a-c. Among the products, 1b-(S), 1b-(R), 2a-(14aS,15S), 2a-(14aR,15R), and 2b were synthesized for the first time.
Keywords:Phenanthroquinolizidine alkaloids   Synthesis   Parham-type cycliacylation
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