The reaction of 1-silylcyclopropyl anions with dichloromethyl methyl ether: the efficient synthesis of cyclopropyl silyl ketones via cyclopropylidene derivatives |
| |
Authors: | Toshiaki Nishizawa Ko-Ki Kunimoto |
| |
Institution: | Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan |
| |
Abstract: | The reaction of 1-silylcyclopropyl anions with dichloromethyl methyl ether is described. The reaction with an excess amount of dichloromethyl methyl ether gives the corresponding cyclopropyl silyl ketones in low yields. On the other hand, the reaction under basic conditions proceeded smoothly to afford the corresponding cyclopropylidene derivatives, exclusively. The resulting cyclopropylidene compounds are subjected to hydrolysis or trapping with electrophiles easily to give the cyclopropyl silyl ketone derivatives in good yields. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|