Total synthesis of motualevic acids A-E |
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| Authors: | Gangarajula Sudhakar Vilas D Kadam Vaddu VN Reddy |
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| Institution: | Organic Chemistry Division-II, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India |
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| Abstract: | The first total synthesis of motualevic acids A-E, isolated from Siliquariaspongia sp., starting from commercially available 1,10-decanediol, is described. The key steps in the synthetic sequence involve stereoselective olefination, Corey-Fuchs reaction, and amide coupling. |
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