An effective aza-Michael addition of aromatic amines to electron-deficient alkenes in alkaline Al2O3 |
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| Authors: | Xin Ai Jin-ming Liu |
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| Affiliation: | State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, PR China |
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| Abstract: | Aza-Michael addition of aromatic or aliphatic amines with various electron-deficient alkenes was performed using alkaline Al2O3 as solid media at room temperature afforded the corresponding Michael addition products in good to excellent yields. The alkaline Al2O3 can be easily recovered and reused. |
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| Keywords: | Aza-Michael addition Aromatic amines Aliphatic amines Alkaline Al2O3 Solvent-free |
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