A paradigm for biological sulfur transfers via persulfide groups: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis |
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| Authors: | Wright Chapman M Palenchar Peter M Mueller Eugene G |
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| Affiliation: | Department of Chemistry & Biochemistry, University of fn2Delaware, Newark, Delaware 19716, USA. |
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| Abstract: | In support of the key features of sulfur transfer in the proposed mechanisms of 4-thiouridine generation, the enzyme ThiI can turn over only once in the absence of reductants of disulfide bonds, and Cys-456 of ThiI receives the sulfur transferred from the persulfide group of the sulfurtransferase IscS. |
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