Multifunctional, biocompatible supramolecular hydrogelators consist only of nucleobase, amino acid, and glycoside |
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Authors: | Li Xinming Kuang Yi Shi Junfeng Gao Yuan Lin Hsin-Chieh Xu Bing |
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Affiliation: | Department of Chemistry, Brandeis University, Waltham, Massachusetts 02454, USA. |
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Abstract: | The integration of nucleobase, amino acid, and glycoside into a single molecule results in a novel class of supramolecular hydrogelators, which not only exhibit biocompatibility and biostability but also facilitate the entry of nucleic acids into cytosol and nuclei of cells. This work illustrates a simple way to generate an unprecedented molecular architecture from the basic biological building blocks for the development of sophisticated soft nanomaterials, including supramolecular hydrogels. |
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