A concise and convergent synthesis of PA-824 |
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| Authors: | Marsini Maurice A Reider Paul J Sorensen Erik J |
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| Institution: | Department of Chemistry, Frick Chemical Laboratory, Princeton University, Princeton, New Jersey 08544, United States. |
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| Abstract: | An efficient four-step synthesis of PA-824, a promising antituberculosis drug candidate, has been developed. This concise approach offers significant improvements over the synthetic route currently used for large-scale production. |
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