Asymmetric allylic alkylation of isatin-derived morita-baylis-hillman carbonates with nitroalkanes |
| |
| Authors: | Guo-Ying Chen Fangrui Zhong Yixin Lu |
| |
| Institution: | Department of Chemistry & Medicinal Chemistry Program, Life Sciences Institute, National University of Singapore , 3 Science Drive 3, Republic of Singapore, 117543. |
| |
| Abstract: | A stereoselective allylic alkylation of isatin-derived Morita-Baylis-Hillman (MBH) carbonates with nitroalkanes has been developed. In the presence of 10 mol % β-isocupreidine (β-ICD), 3,3'-disubstituted oxindoles were prepared with moderate diastereoselectivities and excellent enantioselectivities. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
