贫电子环丙烷衍生物与胂叶立德的反应研究

The reaction of electron-deficient cyclopropane derivatives, cis-1-methoxycarbonyl-2-aryl-6,6-dimethyl-5,7dioxospiro2,5]octa-4,8-diones with benzoylmethylenetriphenylarsorane (2) and methoxycarbonylmethylenetriphenylarsorane (4) was found to form cis,trans-l-methoxycarbonyl-2-aryl-3-benzoyl-7,7-dimethyl-6,8-dioxospiro3,5]nona-5,9-dione (3a-3e) and trans,cis,trans-5-2‘-methoxycarbonyl-2‘-(triphenylarsoranylidene)acetyl]-6oxo-3-aryl-tetrahydro-pyran-2,4-dicarboxylic acid dimethyl esters (5a-5c) respectively with high stereoselectivity. The possible reaction mechanisms for the formation of the different products were also orooosed.

Study on the Reaction of Electron‐deficient Cyclopropane Derivatives with Arsonium Ylides

The reaction of electron‐deficient cyclopropane derivatives, cis‐1‐methoxycarbonyl‐2‐aryl‐6,6‐dimethyl‐5,7‐dioxospiro2,5]octa‐4,8‐diones with benzoylmethylenetriphenylarsorane ( 2 ) and methoxycarbonylmethylene‐triphenylarsorane ( 4 ) was found to form cis,trans‐1‐methoxycarbonyl‐2‐aryl‐3‐benzoyl‐7,7‐dimethyl‐6,8‐dioxo‐spiro3,5]nona‐5,9‐dione ( 3a – 3e ) and trans, cis,trans‐5‐2′‐methoxycarbonyl‐2′‐(triphenylarsoranylidene)acetyl]‐6‐oxo‐3‐aryl‐tetrahydro‐pyran‐2,4‐dicarboxylic acid dimethyl esters ( 5a – 5c ) respectively with high stereoselectivity. The possible reaction mechanisms for the formation of the different products were also proposed.