Cis-Cycloprolylprolin-Anion-ein konfigurationsstabiles Carbanion |
| |
Authors: | Prof Dr Ulrich Schmidt Alexej Nikiforov |
| |
Institution: | 1. Organisch-Chemischen Institut der Universit?t Wien, W?hringer Stra?e 38, A-1090, Wien, ?sterreich
|
| |
Abstract: | The racemisation ofcyclo-(l-Pro?l-Pro) (2) with metal amides in liq. ammonia was examined. The K-kation causes more extensive racemisation than Na-kation, which in turn is more effective than Li+. This, the racemisation of2 int-butyl alcohol with K+C6H5O? and the data gained from corresponding deuterated medium show that the racemisation of2 proceeds in two steps: in the first, the less stabletrans-cyclo-(l-Pro?d-Pro) (3) is formed, followed by the rapid conversion of3 to a mixture ofcyclo-(l-Pro?l-Pro) andcyclo-(d-Pro?d-Pro) in the second step. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|