| 烷基取代三唑硫酮席夫碱的合成和生物活性研究 |
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| 引用本文： | 孙晓红,陶燕,刘源发,贾婴琦,陈邦,杨建武.烷基取代三唑硫酮席夫碱的合成和生物活性研究[J].有机化学,2008,28(1):155-159. |
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| 作者姓名： | 孙晓红 陶燕 刘源发 贾婴琦 陈邦 杨建武 |
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| 作者单位： | 1. 西北大学化工学院化学研究所,西安,710069
2. 西北大学化学系,西安,710069 |
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| 摘 要： | 用5-烷基-4-氨基-2,4-二氢-1,2,4-三唑-3-硫酮与取代芳醛在酸催化下反应合成了7个席夫碱, 化合物结构用1H NMR, IR和元素分析进行了表征, 对植物病原菌的生物活性测试表明它们具有较好的生物活性.
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| 关 键 词： | 三唑硫酮 2 4-二氢-1 2 4-三唑-3-硫酮 合成 生物活性 |
| 收稿时间： | 2007-01-31 |
| 修稿时间： | 2007-08-08 |
Synthesis and Biological Activities of N-(5-Alkyl-2,4-dihydro-3-thioxo-1,2,4-triazol-4-yl) Schiff Bases |
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| SUN,Xiao-Hong,TAO,Yan,LIU,Yuan-Fa,JIA,Ying-Qi,CHEN,Bang,YANG,Jian-Wu.Synthesis and Biological Activities of N-(5-Alkyl-2,4-dihydro-3-thioxo-1,2,4-triazol-4-yl) Schiff Bases[J].Chinese Journal of Organic Chemistry,2008,28(1):155-159. |
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| Authors: | SUN Xiao-Hong TAO Yan LIU Yuan-Fa JIA Ying-Qi CHEN Bang YANG Jian-Wu |
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| Institution: | (College of Chemical Engineering, Chemical Research Institute, Northwest Univer-sity, Xi'an 710069)(Department of Chemistry, Northwest University, Xi'an 710069) |
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| Abstract: | Seven Schiff bases have been prepared by an acid catalyzed condensation of 5-alkyl-4-amino- 2,4-dihydro-1,2,4-triazole-3-thione with substituted aromatic aldehydes, the structures of which have been confirmed by ^1H NMR, IR spectra and elemental analysis. Their biological activities to several vegetable pathogens have been tested, showing that they exhibited good fungicidal activities. |
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| Keywords: | Schiff base 2 4-dihydro-1 2 4-triazole-3-thione synthesis biological activity |
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