Gamma-rays from Mössbauer sources: a low-dose approach to cancer therapy |
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| Authors: | I Ortalli G Pedrazzi K Jiang X Zhang C Carlo-Stella V Rizzoli |
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| Institution: | (1) Istituto di Scienze Fisiche dell'Università, Via M. D'Azeglio 85, 43100 Parma, Italia;(2) Cattedra di Ematologia, Centro Trapianti di Midollo Osseo, Via Gramsci 14, Parma, Italia;(3) Present address: Department of Physics, East China Normal University, Shanghai, China;(4) Present address: Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China |
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| Abstract: | Summary A new approach to cancer treatment using low-energy gamma-rays is discussed. Cultures of bone marrow mononuclear cells collected
from normal donors and patients with chronic myelogenous leukaemia have been studied after the addition of hematin, at different
concentrations, and irradiation by a M?ssbauer gamma-ray source. Growth stimulation has been observed when hematin is added
to normal bone marrow cultures, while growth inhibition is observed when hematin is added to leukaemic cultures. The effect
becomes then more pronounced when hematin is used in combination with M?ssbauer gamma-rays. |
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| Keywords: | Biological effects of radiations PACS 33 45 M?ssbauer spectra |
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