Optimization of L-Lactic acid production from glucose by Rhizopus oryzae ATCC 52311 |
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Authors: | Ying Zhou José M Domínguez Ningjun Cao Jianxin Du George T Tsao |
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Institution: | (1) Laboratory of Renewable Resources Engineering, Purdue University, 47 907 West Lafayette, IN |
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Abstract: | The effect of nutrients on L(+)-lactic acid production from glucose was investigated using Rhizopus oryzae ATCC 523 11. From the shake-flask experiments, the optimal medium composition was defined for improved lactic-acid production.
In order to enhance lactic-acid production rate and product yield, controlled aeration in a bubble column was conducted under
optimal conditions. Results showed a maximum lactic-acid production rate of 2.58 g/L/h was obtained with an initial glucose
concentration of 94 g/L. Finallactic-acid concentration of 83 g/L was achieved after 32 h of fermentation with a weight of
0.88 glactic acid/g glucose consumed. |
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Keywords: | Bubble column lactic acid Rhizopus oryzae |
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