Encapsulation of proteins by Electro Hydro Dynamic Atomization |
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| Authors: | Tomasz Ciach |
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| Affiliation: | Faculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego st. 1, 00-645 Warsaw, Poland |
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| Abstract: | Summary: Aerosol reactor for Electro Hydro Dynamic Atomization has been used to encapsulate water soluble proteins in poly(ε-caprolactone). As a raw material w/o emulsion of BSA water solution emulsified in the organic solution of polymer was applied. Stability of the spraying process itself for particles production was investigated. Also raw material emulsion stability has been examined and emulsion stabiliser has been found. Protein release rate from produced particles was determined. |
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| Keywords: | biodegradable polymers drug delivery systems electrospray emulsion poly(ε-caprolactone) |
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