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Ruthenium-catalysed conversion of oxime ethers into nitriles |
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| Authors: | Naveen Anand Alexandra J Parker Jonathan MJ Williams |
| Institution: | a Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY, UK b Process Research and Development, AstraZeneca, Avlon Works, Severn Road, Hallen, Bristol BS10 7ZE, UK |
| Abstract: | The conversion of oxime ethers into nitriles has been achieved under neutral conditions using Ru(CO)(PPh3)3H2 and the bidentate ligand Xantphos as the catalyst. |
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