| CHEMOTHERAPEUTIC POLYMERS. THE SYNTHESIS OF POLYMERS CONTAINING 5-FLUOROURACIL IN THE MAIN CHAIN |
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| 作者姓名： | 卓仁禧 叶大铿 刘高伟 刘振华 王宣 |
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| 作者单位： | Department of Chemistry，Wuhan University，Wuhan，Department of Chemistry，Wuhan University，Wuhan，Department of Chemistry，Wuhan University，Wuhan，Department of Chemistry，Wuhan University，Wuhan，Department of Chemistry，Wuhan University，Wuhan |
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| 摘 要： | 1,3-Dialkyl-5-fluorouracil compounds and polymers containing 5-fluorouracil in the main chain were synthesized by the reaction of 5-fluorouracil with alkylbromidcs and polymethylene bromides respectively. The structures of the new compounds and polymers were confirmed by IR and NMR spectra as well as elemental analyses.The factors affecting the polycondensation, such as the temperature and time of the reaction were investigated. The anti-tumor activity of some of the 5-fluorouracil containing compounds and polymers were also measured.
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| 收稿时间： | 1983-01-24 |
CHEMOTHERAPEUTIC POLYMERS. THE SYNTHESIS OF POLYMERS CONTAINING 5-FLUOROURACIL IN THE MAIN CHAIN* |
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| ZHUO Renxi,YE Dakeng,LIU Gaowei,LIU Zhenhua,WANG Xuan.CHEMOTHERAPEUTIC POLYMERS. THE SYNTHESIS OF POLYMERS CONTAINING 5-FLUOROURACIL IN THE MAIN CHAIN[J].Chinese Journal of Polymer Science,1984,0(1):7-11. |
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| Authors: | ZHUO Renxi YE Dakeng LIU Gaowei LIU Zhenhua WANG Xuan |
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| Institution: | Department of Chemistry; Wuhan University; Wuhan |
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| Abstract: | 1,3-Dialkyl-5-fluorouracil compounds and polymers containing 5-fluorouracil in the main chain were synthesized by the reaction of 5-fluorouracil with alkylbromidcs and polymethylene bromides respectively. The structures of the new compounds and polymers were confirmed by IR and NMR spectra as well as elemental analyses. The factors affecting the polycondensation, such as the temperature and time of the reaction were investigated. The anti-tumor activity of some of the 5-fluorouracil containing compounds and polymers were also measured. |
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