| Synthesis and Antimicrobial Properties of the Novel Fluonnated Bis-ammonium Salts with Two Primary Amine Groups |
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| 引用本文： | Jian Bin LUO,Qiang WANG,Hong TAN,Jie Hua LI,Yin Ping ZHONG College of Polymer Science and Engineering,Sichuan University,Chengdu 610065 College of Chemistry & Environment Protection Engineering,Southwest University for Nationalities,Chengdu 610041 Key Laboratory of Bio-resources and Eco-environment (Ministry of Education),College of Life Sciences,Sichuan University,Chengdu 610064. Synthesis and Antimicrobial Properties of the Novel Fluonnated Bis-ammonium Salts with Two Primary Amine Groups[J]. 中国化学快报, 2006, 0(11) |
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| 作者姓名： | Jian Bin LUO Qiang WANG Hong TAN Jie Hua LI Yin Ping ZHONG College of Polymer Science and Engineering Sichuan University Chengdu 610065 College of Chemistry & Environment Protection Engineering Southwest University for Nationalities Chengdu 610041 Key Laboratory of Bio-resources and Eco-environment (Ministry of Education) College of Life Sciences Sichuan University Chengdu 610064 |
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| 摘 要： | In order to resolve the increasing resistance phenomena of the Gram-negative bacteria against single chain quaternary ammonium salts (QAS), lysine with a pedant fluorinated bis-ammonium salts was synthesized and its antimicrobial properties were evaluated in this work. The novel fluorinated bis-ammonium salts shows similar activity with conventional single chain quaternary ammonium salts against Gram-positive bacteria but stronger activity against Gram-negative bacteria and yeast compared with the single chained counterpart.
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Synthesis and Antimicrobial Properties of the Novel Fluonnated Bis-ammonium Salts with Two Primary Amine Groups |
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| Jian Bin LUO,Qiang WANG,Hong TAN,Jie Hua LI,Yin Ping ZHONG College of Polymer Science and Engineering,Sichuan University,Chengdu College of Chemistry , Environment Protection Engineering,Southwest University for Nationalities,Chengdu Key Laboratory of Bio-resources and Eco-environment. Synthesis and Antimicrobial Properties of the Novel Fluonnated Bis-ammonium Salts with Two Primary Amine Groups[J]. Chinese Chemical Letters, 2006, 0(11) |
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| Authors: | Jian Bin LUO Qiang WANG Hong TAN Jie Hua LI Yin Ping ZHONG College of Polymer Science Engineering Sichuan University Chengdu College of Chemistry & Environment Protection Engineering Southwest University for Nationalities Chengdu Key Laboratory of Bio-resources Eco-environment |
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| Affiliation: | Ministry of Education |
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| Abstract: | In order to resolve the increasing resistance phenomena of the Gram-negative bacteria against single chain quaternary ammonium salts (QAS), lysine with a pedant fluorinated bis-ammonium salts was synthesized and its antimicrobial properties were evaluated in this work. The novel fluorinated bis-ammonium salts shows similar activity with conventional single chain quaternary ammonium salts against Gram-positive bacteria but stronger activity against Gram-negative bacteria and yeast compared with the single chained counterpart. |
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| Keywords: | Antimicrobial agents fluorinated bis-ammonium salts primary amine groups |
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