The synthesis of fluorinated materials in microreactors |
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| Authors: | Kouichi Kawai |
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| Affiliation: | Graduate School of Bioscience & Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226 8501, Japan |
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| Abstract: | Synthetic utilities of microreactor for the synthesis of fluorinated materials are described. In particular, synthesis of silylenol ether of 4,4,4-trifluorobutan-2-one and its synthetic application at room temperature. Further, nitroaldol reactions and Michael addition reaction in microreactor are convenient ways for the syntheses of difluoromethylated materials. |
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| Keywords: | 4,4,4-Trifluorobutan-2-one Microreactor Nitroaldol reaction |
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