Centro di Studio per la Chimica del Farmaco del C.N.R., Istituto di Chimica Farmaceutica dell' Università, 00185 Roma, Italy
Abstract:
The title process has been accomplished by a three-step sequence involving protection of aldehyde as the imine, reduction of ketone with lithium tri--butoxyaluminohydride, and regeneration of aldehyde on hydrolytic work-up.