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Synthesis of acridines from diphenylamine-2-carboxaldehydes prepared via the mcfadyen-stevens reaction |
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| Authors: | Harold Graboyes Elvin L. Anderson Sidney H. Levinson Theodore M. Resnick |
| Abstract: | A general synthesis of acridines has been developed using diphenylamine-2-carboxaldehydes. Diphenylamine-2-carboxylic acids are converted to their p-toluenesulfonylhydrazides which are decomposed using a modified McFadyen-Stevens reaction to yield an aldehyde derivative which affords the acridine upon treatment with mineral acid. |
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