Chitosan and radiation chemistry |
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| Authors: | Andrzej G Chmielewski |
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| Institution: | 1. University Institute of Chemical Technology, North Maharashtra University, Jalgaon, 425001, India;2. Molecular Biology and Genetic Engineering Section, Vasantdada Sugar Institute, Manjari (Bk.), Pune, 412307, India;3. Tissue Culture Section, Vasantdada Sugar Institute, Manjari (Bk.), Pune, 412307, India;4. Plant Stress Physiology and Biotechnology Section, Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400085, India;1. Key Laboratory Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China;2. Qingdao University of Science & Technology, Qingdao, 266042, China;1. Department Biophysics, Faculty of Science, Cairo University, Giza, Egypt;2. Department of Physics, Faculty of Dentistry, MSA University, 6 of October, Egypt;1. Department of Food Nutrition and Health Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan;2. Division of Radiation Oncology, Department of Medicine, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan;3. Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan;4. Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan;5. Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan;6. Advanced Membrane Materials Center, National Taiwan University of Science and Technology, Taipei, Taiwan;7. R&D Center for Membrane Technology, Chung Yuan Christian University, Zhongli District, Taoyuan City, Taiwan;8. Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar – 608002, Tamil Nadu, India;9. Big Data Center, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan;10. Department of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung, Taiwan |
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| Abstract: | Chitosan as a raw material with special properties has drawn attention of scientists working in the field of radiation processing and natural polymer products development, and also of specialists working in the field of radiation protection and oncologists. Especially the applications concern reduced molecular weight chitosan which still retain its chemical structure; such form of the compound is fostering biological, physical and chemical reactivity of the product. Chitosan degrades into fragments under γ-ray or electron beam irradiation. Antibacterial properties of the product are applied in manufacturing hydrogel for wound dressing and additional healing properties can be achieved by incorporating in the hydrogel matrix chitosan bonded silver clusters. Another possible application of chitosan is in reducing radiation damage to the radiation workers or radiation cured patients. In the case of radioisotopes oral or respiratory chitosan-based materials can be applied as chelators. Applications of chitosan in oncology are also reported. |
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