Study of Pt/TiO2 nanocomposite for cancer-cell treatment |
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| Authors: | Lei Liu Peng Miao Yuanyuan Xu Zhipeng Tian Zhigang Zou Genxi Li |
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| Institution: | 1. Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China;2. Eco-Materials and Renewable Energy Research Center, Department of Physics, Nanjing University, Nanjing 210093, PR China;3. Laboratory of Biosensing Technology, School of Life Science, Shanghai University, Shanghai 200444, PR China |
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| Abstract: | The increasing incidence of cancer all over the world demands new, effective and secure materials for treatment. In this paper, we propose Pt/TiO2 nanocomposite for cancer-cell treatment because noble metal nanoparticles are supposed to enhance the photocatalytic activity of TiO2 nanoparticles. To evaluate the cancer-cell killing effect of our Pt/TiO2 nanocomposite, TiO2 and Au/TiO2 nanoparticles are also introduced. The prepared Pt/TiO2 nanocomposite are characterized with transmission electron microscopy (TEM) and UV–vis adsorption spectra. Results of cell treatment indicate that Pt/TiO2 nanocomposite, as extremely stable metal–semiconductor nanomaterial, can exhibit a very high photodynamic efficiency under a mild ultraviolet radiation. And our Pt/TiO2 nanocomposite shows to be more effective in cancer-cell treatment than TiO2 and Au/TiO2 nanoparticles. As a result, Pt/TiO2 nanocomposite may be supposed to have a promising application for cancer-cell treatment. |
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