Reaction of 2-amino-5-h alop yridines with methyl acrylate |
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Authors: | R. S. Baltrushis Z. -I. G. Beresnevichyus |
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Affiliation: | (1) Kuanas Polytechnical Institute, USSR |
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Abstract: | Two isomeric bicyclic dihydropyridopyrimidinones (II and IV), the methyl esters of the corresponding N-pyridyl--alanines (V), and a number of other compounds are formed during the reaction of methyl acrylate with 2-amino-5-halopyridines in the presence of acid catalysts. Compounds II and IV were hydrolytically cleaved, and some derivatives of N-(5-halo-2-pyridyl)--alanines were obtained.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 215–219, February, 1971. |
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