Imidazole-modified porphyrin as a pH-responsive sensitizer for cancer photodynamic therapy |
| |
| Authors: | Zhu Xianchun Lu Wentong Zhang Yazhou Reed Aisha Newton Brandon Fan Zhen Yu Hongtao Ray Paresh C Gao Ruomei |
| |
| Institution: | Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS 39211, USA. |
| |
| Abstract: | 5,10,15,20-Tetrakis(N-(2-(1H-imidazol-4-yl)ethyl)benzamide)porphyrin produced twice as many singlet oxygen ((1)O(2)) molecules at pH 5.0 (quantum yield 0.53 ± 0.01) than at pH 7.4, whereas the (1)O(2) quenching rate was reduced by a factor of 2.5 for a pH change from 7.4 to 5.0. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
