Synthesis,Crystal Structure and Antimicrobial Property of 4-Bromo- 2- [（3-methypyridin-2-ylimino）methyl]phenol

The title Schiff base compound 4-bromo-2-（3-methylpyridin-2-ylimino）methyl]phenol was prepared and structurally characterized by elemental analysis, IR spectrum, and single-crystal X-ray diffraction. The crystal belongs to monoclinic, space group P2 1/n, with a = 4.4870（9）, b = 19.953（4）, c = 13.860（3）A, β = 93.13（3）°, V = 1239.0（4）A3 Z = 4, Dc = 1.561 g/cm3, C13H11BrN2O2 , Mr = 291.15, p = 3.302 mm-1 and F（000） = 584. The final refinement gave R = 0.0608 and wR = 0.1377 for 1329 observed reflections with I 〉 2σ（I）. X-ray diffraction reveals that the non-hydrogen atoms in the compound are nearly coplanar, with the mean deviation of 0.0197A from the plane. The molecule adopts an E configuration about the central C=N functional bond. The compound possesses moderate antimicrobial property.

Synthesis, Crystal Structure and Antimicrobial Property of 4-Bromo-2-[(3-methypyridin-2-ylimino)methyl]phenol

The title Schiff base compound 4-bromo-2-(3-methylpyridin-2-ylimino)me- thyl]phenol was prepared and structurally characterized by elemental analysis, IR spectrum, and single-crystal X-ray diffraction. The crystal belongs to monoclinic, space group P21/n, with a = 4.4870(9), b = 19.953(4), c = 13.860(3), β = 93.13(3)o, V = 1239.0(4) 3, Z = 4, Dc = 1.561 g/cm3, C13H11BrN2O2, Mr = 291.15, μ = 3.302 mm-1 and F(000) = 584. The final refinement gave R = 0.0608 and wR = 0.1377 for 1329 observed reflections with I > 2σ(I). X-ray diffraction reveals that the non-hydrogen atoms in the compound are nearly coplanar, with the mean deviation of 0.0197  from the plane. The molecule adopts an E configuration about the central C=N functional bond. The compound possesses moderate antimicrobial property.