Syntheses based on 8-substituted 3-bromoacetyl-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones |
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Authors: | T V Kochikyan E V Harutyunyan V S Harutyunyan A A Avetisyan |
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Institution: | (1) Chemistry Department, Yerevan State University, Yerevan, 375025, Republic of Armenia |
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Abstract: | By reaction of 8-substituted 3-bromoacetyl-3,8-dimethyl-2,7-dioxaspiro4,4]nonane-1,6-diones with thiourea and substituted
thioureas under Hansch reaction conditions, we have obtained the novel heterocycles 3-2′-amino(arylamino)thiazol-4-yl]-3,8-dimethyl-2,7-dioxaspiro4,4]nonane-1,6-diones.
By reacting the above-indicated bromoacetyl spirodilactones with 5-aryl-3-mercapto-1,2,4-triazoles, we obtained 8-substituted
3-(aryl-3,8-dimethyl-1′,2′,4′-triazol-3′-yl)thioacetyl-2,7-dioxaspiro4,4]nonane-1,6-diones.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 123–129, January, 2006. |
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Keywords: | aminothiazoles bromoacetyl lactones spirodibutanolides triazoles |
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