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Global stability of an SAIRS epidemic model with vaccinations,transient immunity and treatment
Abstract:We consider an SAIRS epidemic model with vaccinations and treatment, where asymptomatic and symptomatic infectious individuals are considered in the transmission of the disease. We found the basic reproduction number, 0 and using 0, we conducted global stability analysis. We proved when 0<1, the disease-free equilibrium is globally stable. If 0>1, the disease-free equilibrium in unstable and a unique endemic equilibrium exists. We explored the global stability of the endemic equilibrium and noticed it is globally stable under certain conditions. Moreover, we then considered a special case of the SAIRS model, the SAIR model. We proved the disease-free equilibrium is globally stability when 0<1 and the endemic equilibrium is globally stable when 0>1. Next, we numerically simulated our analytical results and plotted these for various cases. Finally, we performed sensitivity analysis to tell us how each parameter in the system affects disease transmission.
Keywords:Global stability  Lyapunov functions  Geometric approach  Vaccinations  Treatment
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