Surface modification of resorcinarene based self-assembled solid lipid nanoparticles for drug targeting |
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| Authors: | Ehrler Stefan Pieles Uwe Wirth-Heller Amina Shahgaldian Patrick |
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| Institution: | University of Applied Sciences Northwestern Switzerland, School of Life Sciences, Institute of Chemistry and Bioanalytics, Gründenstrasse 40, 4132 Muttenz, Switzerland. |
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| Abstract: | Prolyl-bearing amphiphilic resorcinarenes, e.g. tetrakis(N-methylprolyl)tetraundecylcalix4]resorcinarene, self-assemble as stable solid lipid nanoparticles; these fully characterized systems could be further functionalized at their surface with proteins, and interact with specific antibodies bound on a sensor surface. |
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