Biocompatibility of the Ti81Nb13Ta3Zr3 Alloy |
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| Authors: | M. A. Sevostyanov A. S. Baikin L. A. Shatova E. O. Nasakina A. V. Berezhnov S. V. Gudkov K. V. Sergienko S. V. Konushkin M. I. Baskakova A. G. Kolmakov |
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| Affiliation: | 1.Baikov Institute of Metallurgy and Materials Science,Russian Academy of Sciences,Moscow,Russia;2.Voronezh State Technical University (VSTU),Voronezh,Russia;3.Institute of Cell Biophysics,Russian Academy of Sciences,Pushchino,Russia;4.Prokhorov General Physics Institute,Russian Academy of Sciences,Moscow,Russia;5.Vladmirsky Moscow Regional Research and Clinical Institute (MONIKI),Moscow,Russia;6.All-Russian Research Institute of Phytopathology,Russian Academy of Agricultural Sciences,Bolshie Vyaziomy,Russia |
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| Abstract: | Titanium-based alloy with low-toxic metals such as niobium, tantalum and zirconium (TiNbTaZr) was manufactured. The primary weight percentages of elements used for fusion were: titanium, 65%; niobium, 20%, tantalum, 10%; and zirconium, 5%. The TiNbTaZr alloy had a yield strength of about 550 MPa, a tensile strength of about 700 MPa, and a Young’s modulus of about 50 GPa, that is, it was comparable with Nitinol. A primary study of the biocompatibility of the TiNbTaZr alloy using the SH-SY5Y cells showed that the alloy did not have significant short-term toxicicity towards the cells incubated on the alloy surface. The number of non-viable cells was 2.5 times lower on the TiNbTaZr alloy than on Nitinol. The biocompatibility of TiNbTaZr was more pronounced than that of the Nitinol reference sample. |
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