Ensemble hybridisation--a new method for exploring sequence dependent fluorescence of dye-nucleic acid conjugates |
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| Authors: | Köhler Olaf Jarikote Dilip Venkatrao Seitz Oliver |
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| Institution: | Institut für Chemie, Humboldt-Universit?t zu Berlin, Brook-Taylor-Strasse 2, D-12489 Berlin, Germany. |
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| Abstract: | The fluorescence of thiazole orange as artificial base in PNA was investigated in a nearest neighbour analysis; library-to-library hybridisation allowed the identification of probe sequences suitable for homogeneous DNA detection. |
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