| Application of Genetic Algorithm to the QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcription Inhibitors |
| |
| 引用本文： | Ting Jun HOU, Jun Mei WANG, You Yong LI, Xiao Jie XU(Chemistry department,Beida-Jiuyuan Molecular Design Laboratory,Peking University,Beijing 100871). Application of Genetic Algorithm to the QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcription Inhibitors[J]. 中国化学快报, 1998, 0(7) |
| |
| 作者姓名： | Ting Jun HOU Jun Mei WANG You Yong LI Xiao Jie XU(Chemistry department Beida-Jiuyuan Molecular Design Laboratory Peking University Beijing 100871) |
| |
| 作者单位： | Chemistry department，Beida-Jiuyuan Molecular Design Laboratory，Peking University，Beijing 100871 |
| |
| 摘 要： | Quantitativestructure-activityrelationship(QSAR)modelingprovidesarationalbasisforunderstandingmechanismsofbiologicalperformanceandformodifyingchemicalstfucturetoimProveperformancebyaltCringchemicalstIuctllre.Itiswellknownthatoneofthemostimportantanddiffcultproblemintraditionalquantitativestructure-activityrelationshipistheproperchoiceoftheadequatefeaturesforbuildingtheregressionmodels.Recentlysomereportssuggestthatgeneticalgorithms(GA)maybeusefulinQSARanalysis.WehavedevelopedaQSARprogra…
|
Application of Genetic Algorithm to the QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcription Inhibitors |
| |
| Ting Jun HOU, Jun Mei WANG, You Yong LI, Xiao Jie XU. Application of Genetic Algorithm to the QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcription Inhibitors[J]. Chinese Chemical Letters, 1998, 0(7) |
| |
| Authors: | Ting Jun HOU Jun Mei WANG You Yong LI Xiao Jie XU |
| |
| Abstract: | |
| |
| Keywords: | QSAR GA(genetic algorithm) HIV |
| 本文献已被 CNKI 等数据库收录！ |
