光学多普勒层析三维矢量测速方法研究

光学多普勒层析术(ODT)是一种高分辨、非侵入的生物医学成像手段,能同时得到组织的结构信息和组织内血管的流速信息.提出了一种新型的基于相位分辨技术的ODT三维矢量测速方法.在ODT系统样品臂的准直镜和聚焦透镜之间加入窄带相位片,形成三个不同的相位延迟,通过计算多普勒频移和不同相位延迟下的多普勒展宽,可得到毛细管内的三维矢量流场分布.对已知浓度的聚苯乙烯溶液进行了一系列不同角度和不同流速的实验,结果证明这种新型的ODT矢量测速方法可以较精确的实现三维矢量流速的测量.

Three-Dimensional Vector Velocity Measurement in Optical Doppler Tomography

Optical Doppler tomography (ODT) is a high-resolved and non-invasive biomedical imaging technique,which can obtain tissue structure and blood flow velocity at the same time. A novel phase-resolved ODT method to measure three-dimensional vector velocity is presented. After inserting the designed narrowband phase plate between the collimator and focusing lens of the sample arm, three different phase retardations are formed. By calculating the Doppler shift and the Doppler bandwidth relative to the three phase retardations, three-dimensional vector velocity distribution of the solution inside the capillary is obtained. Several experiments of polystyrene solution with different angle setup and variational flow velocity are conducted, and the results demonstrate the feasibility of this method to measure three-dimensional vector velocity.