One-Pot Three-Component Synthesis of 3-Aminoimidazo[1,2-a]pyridines and -pyrazines in the Presence of Silica Sulfuric Acid |
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| Authors: | Ahmad Shaabani Ebrahim Soleimani Ali Maleki |
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| Affiliation: | (1) Department of Chemistry, Shahid Beheshti University, Tehran, Iran |
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| Abstract: | Summary. The synthesis of 3-aminoimidazo[1,2-a]pyridines and 3-aminoimidazo[1,2-a]pyrazines through a condensation reaction of 2-aminopyridine or 2-aminopyrazine, aldehyde, and alkyl or aryl isocyanide in high yields at room temperature in the presence of silica sulfuric acid is described. |
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| Keywords: | . Multi-component reaction Isocyanide 3-Aminoimidazo[1,2-a]pyridine 3-Aminoimidazo[1,2-a]pyrazine Silica sulfuric acid. |
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