Construction of the azocane (azacyclooctane) moiety of the Lycopodium alkaloid lycopladine H via an intramolecular hydroaminomethylation strategy |
| |
Authors: | Sacher Joshua R Weinreb Steven M |
| |
Institution: | Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA. |
| |
Abstract: | An efficient synthetic strategy has been developed for annulation of an azocane ring onto a bicyclo2.2.2]octane scaffold via an intramolecular hydroaminomethylation protocol to generate an advanced intermediate bearing three of the four rings of the structurally unique Lycopodium alkaloid lycopladine H (1). |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|