The electrochemical and spectroelectrochemical behaviors of SOD at cysteine modified gold electrode.

Different promoters were used to enhance the rate of the electron transfer process of superoxide dismutase (SOD). A quasi-reversible cyclic voltammogram (CV) of SOD was observed on the cysteine-modified gold wire electrode. The coupled adsorption/desorption processes and the characteristic Raman spectra of different states of SOD molecules on the electrode surface were studied with electrochemical quartz crystal microbalance (EQCM) and in-situ Raman spectroelectrochemical techniques. The possible promotion mechanism was discussed.