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A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions |
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| Authors: | Kalyan Kumar PasunootiHua Chai Chantel Nixon JensenBala Kishan Gorityala Siming WangXue-Wei Liu |
| Affiliation: | Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore |
| Abstract: | The synthesis of dihydropyrimidinones via a clean multi-component Biginelli reaction under microwave irradiation is reported. The copper-catalyzed process proved to be simple, efficient, economical, and environmentally friendly. |
| Keywords: | Dihydropyrimidinone Green chemistry Biginelli reaction Microwave reaction Multi-component reaction |
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