Dendritic development of <Emphasis Type="Italic">Drosophila</Emphasis>high order visual system neurons is independent of sensory experience |
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Authors: | Email author" target="_blank">Ethan?K?ScottEmail author John?E?Reuter Liqun?Luo |
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Institution: | (1) Department of Biological Sciences, Stanford University, Stanford, CA 94305-5020, USA |
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Abstract: | Background The complex and characteristic structures of dendrites are a crucial part of the neuronal architecture that underlies brain
function, and as such, their development has been a focal point of recent research. It is generally believed that dendritic
development is controlled by a combination of endogenous genetic mechanisms and activity-dependent mechanisms. Therefore,
it is of interest to test the relative contributions of these two types of mechanisms towards the construction of specific
dendritic trees. In this study, we make use of the highly complex Vertical System (VS) of motion sensing neurons in the lobula
plate of the Drosophila visual system to gauge the importance of visual input and synaptic activity to dendritic development. |
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Keywords: | |
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