Evaporation-driven instability of the precorneal tear film |
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| Authors: | Cheng-Chun Peng Colin Cerretani Richard J Braun CJ Radke |
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| Institution: | 1. Department of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, United States;2. Department of Mathematical Sciences, University of Delaware, Newark, DE, 19716, United States;3. Vision Science Group, University of California, Berkeley, CA, 94720, United States |
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| Abstract: | Tear-film instability is widely believed to be a signature of eye health. When an interblink is prolonged, randomly distributed ruptures occur in the tear film. “Black spots” and/or “black streaks” appear in 15 to 40 s for normal individuals. For people who suffer from dry eye, tear-film breakup time (BUT) is typically less than a few seconds. To date, however, there is no satisfactory quantitative explanation for the origin of tear rupture. |
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| Keywords: | Tear-film stability Evaporation Dry eye Hyperosmolarity Tear-film lipid layer |
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