Conditional Response to Stress in Yeast |
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Authors: | Marco Siderius Willem H Mager |
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Institution: | (1) Department of Biochemistry and Molecular Biology, Biocentrum Amsterdam, Faculteit der Exacte Wetenschappen, Vrije Universiteit, NL-1081 HV Amsterdam, The Netherlands, NL |
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Abstract: | Summary. All living cells respond to sudden, adverse changes in their environment by evoking a stress response. Here we focus mainly on the response of the model eukaryotic organism Saccharomyces cerevisiae (baker s yeast) to an increase in external osmolarity. We summarize data demonstrating that stress responses largely depend on the existing environmental growth conditions. Nutrients and other medium parameters such as external pH determine how yeast cells sense osmotic stress circumstances and subsequently elicit adaptive responses. It is likely that the composition of cell wall and plasma membrane plays an important role in this process.Received September 3, 2002; accepted September 13, 2002
Published online May 26, 2003 |
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Keywords: | , Yeast, Stress response, Growth control, High osmolarity, Environmental conditions, |
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