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基因工程中的液相色谱
引用本文:刘彤,耿信笃. 基因工程中的液相色谱[J]. 色谱, 2000, 18(1): 30-34
作者姓名:刘彤  耿信笃
作者单位:西北大学现代分离科学研究所,现代分离科学省重点实验室,陕西,西安,710069
基金项目:国家自然科学基金!资助项目 (2 9675 0 17和 3 9880 0 0 3 )
摘    要: 对液相色谱用于基因工程生产蛋白质分子构象、变性蛋白的复性、蛋白折叠中间体等方面的研究进展,以及液相色谱在基因工程样品的质量 检验、制备方面的新进展分别加以评述。全文引用了42篇文献。

关 键 词:基因工程  液相色谱  计量置换保留模型  质量检验  制备
修稿时间:1998-12-19

The Application of Liquid Chromatography in Genetic Engineering
LIU Tong,GENG Xin-du. The Application of Liquid Chromatography in Genetic Engineering[J]. Chinese journal of chromatography, 2000, 18(1): 30-34
Authors:LIU Tong  GENG Xin-du
Affiliation:Institute of Modern Separation Science, Shaanxi Provincial Key Laboratory of Modern Separation Science, Northwest University, Xi'an 710069, China.
Abstract:The recent development of the molecular conformation,renaturation and intermediates on therapeutic proteins produced in biotechnology is reviewed.It also includs the quality control and in preparation of the therapeutic proteins in large scale by liquid chromatography in down stream technology.This review includes 42 references. The recent development of the molecular conformation,renaturation and intermediates on therapeutic proteins produced in biotechnology is reviewed.It also includs the quality control and in preparation of the therapeutic proteins in large scale by liquid chromatography in down stream technology.This review includes 42 references.
Keywords:genetic engineering  liquid chromatography  stoichiometric displacement model for retention  quality control  preparation
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