Nucleophilic Substitution in 1,5-Benzodiazepin-2-ones |
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| Authors: | V I Bozhanov S P Ivonin |
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| Institution: | (1) Dnepropetrovsk State University, Dnepropetrovsk, 320625, Ukraine |
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| Abstract: | The reaction of 3-bromo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one with cyclic amines gives 3-aminoalkyl-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one. Thiazolo4,5-b]1,5]benzodiazepine was isolated along with the substitution product when thiourea was used. |
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| Keywords: | 1 5-benzodiazepin-2-ones thiazolo[4 5-b][1 5]benzodiazepine bromination phase-transfer catalysis nucleophilic substitution |
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