Ring contraction synthesis of 2,5-disubstituted-3-arylamino-4-cyanopyrroles from 2,6-disubstituted-4-arylamino-5-cyanopyrimidines |
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| Authors: | Stefan Robev |
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| Affiliation: | Department of Pharmacology Faculty of Medicine, Sofia-31, Bulgaria |
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| Abstract: | A method for synthesis of 2,5-disubstituted-3-arylamino-4-cyanopyrroles from newly synthesised 2,6-disubstituted-4-arylamino-5-cyanopyrimidines by treatment with zinc and acetic acid, the yields being up to 80%, is developed. |
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